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If your blood work shows a slight creatinine increase or eGFR decrease in the first few months of semaglutide, do not panic

In the amyloidogenic pathway, APP via and secretases is converted to the neurotoxic A which promote the formation of amyloid plaque

MACE (Major Adverse Cardiovascular Events) : endpoint composito cardiovascolare comunemente utilizzato nei grandi trial di sicurezza, comprendente infarto miocardico non fatale, ictus non fatale e morte cardiovascolare

Im obviously not trying to replicate that format or audience, and I do believe these institutions provide a lot of value, too, BUT I do want to stress that you get access to my analysis and ideas (plus everything else I covered on this blog in the past) for a fraction of that

So when a sprawling telehealth platform like Hers enters the weight loss arena, we don't just see another brand

So, what interventions could be recommended for JM to mitigate his cardiovascular risk