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The study enrolled more than 2,900 patients who had a history of a major atherosclerotic cardiovascular disease event (ASCVD) or who were at an increased risk for such an episode." Merck's PCSK9 pill holds 'significant advantage' with injectable-like cholesterol reductions: analysts fiercebiotech.com To view or add a comment, sign in Breaking from #AHA25 The phase 3 CORALreef HeFH trial brings a major step forward: the first oral PCSK9 inhibitor, enlicitide, cuts LDL-C by 60% vs placebo in adults with heterozygous familial hypercholesterolemia already on maximally tolerated statins

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Graphical Abstract Similar content being viewed by others Introduction Combinational pharmacotherapies provide a promising approach for the treatment of obesity and type 2 diabetes

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