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Verma S, Poulter NR, Bhatt DL et al (2018) Effects of liraglutide on cardiovascular outcomes in patients with type 2 diabetes mellitus with or without history of myocardial infarction or stroke

These participants had baseline HbA1c levels of 9.0% or lower (Supplemental Fig

But for someone with a smaller percentage of their body weight to lose, or with health conditions, compounded medications might introduce unnecessary risk, she said

A network meta-analysis published in the Journal of the Endocrine Society found retatrutide achieved 23.77% weight reduction compared to 16.79% for tirzepatide when standardized across trials, with absolute weight loss of 16.34 kg versus 11.82 kg

doi: 10.1210/endrev/bnz002 43 AmbatiSDuanJHartzellDLChoiYHDella-FeraMABaileCA

FDA-approved doesnt have to mean expensive