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CagriSema: GI adverse events in 79.6% of CagriSema group vs 39.9% placebo in REDEFINE 1

(2012) GLP-1 receptor antagonist exendin-(9-39) elevates fasting blood glucose levels in congenital hyperinsulinism owing to inactivating mutations in the ATP-sensitive K + channel

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van der Westhuizen, E

For that reason, dose strategy should consider systemic hormonal status rather than symptom relief alone
