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Patients diagnosed with diabetes are initiating GLP-1 treatment more quickly than ever before Since 2021, the average time between a diabetes diagnosis and the initiation of a GLP-1 therapy has decreased by about one month, underscoring how quickly these drugs have moved to the forefront of care

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CMSs efforts to expand Medicare coverage of GLP-1s for obesity could provide substantial benefits to millions of Medicare beneficiaries, given the potential demand for these highly effective medicationsThere are potential drawbacks to the short-term program, however.

This review article discusses the potential antidepressant effects of GLP-1RAs, especially in the context of their action on the processes related to neuroprotection, inflammation, stress response, energy metabolism, gut-brain crosstalk and the stability of the gut microbiota