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Weight loss goals should be personalized to each patient and weighed against risks of contributing to sarcopenia
The long-term safety signals from STEP 5 and from the larger SUSTAIN diabetes database are reassuring but not definitive five-year and ten-year data continue to accumulate as more patients enter long-term treatment
This process supports informed prescribing decisions and helps establish appropriate dosing strategies
Injection site reactions Redness, mild swelling, itching, or a small bump at the injection site are common and usually resolve within 24-48 hours
doi: 10.1038/s41586-019-1471-1
