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HPLC-UV measures peptide concentrations based on absorbance at specific wavelengths, while HPLC-MS uses m/z for more precise and sensitive quantification

[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Matsukawa A., Takeda K., Kudo S., Maeda T., Kagayama M., Akira S

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Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials

However, the authors note that substantial weight loss can be accompanied by reductions in lean body mass, underscoring the need for further research into dosing strategies and interventions that preserve muscle while promoting fat loss