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Regulatory reality: Tesamorelins approved-drug status (EGRIFTA) brings a real prescribing label with IGF-1 and glucose monitoring requirements and clear contraindications which is why those safety rules carry over to the research framing here

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The hormone acts simultaneously on the brain (satiety), pancreas (insulin release, glucagon suppression), and stomach (slowed emptying)

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These elevations resolved without intervention in most cases