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It binds both receptors but produces a stronger functional response at GIPR than at GLP-1R compared with the native ligands, which is part of why it behaves differently from a balanced co-agonist

Patients with the PowerPort devices may possibly be at a higher risk of serious complications or injury due to a catheter failure, according to lawsuits filed against the manufacturers of the Bard PowerPort Device

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How peptides work often involves these modifications to overcome the short half-lives of natural peptides

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