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doi: 10.1016/S0140-6736(17)33102-1

To minimise discomfort, eat smaller, more frequent meals, avoid high-fat or spicy foods, and stay well hydrated

Bulk-forming fiber like psyllium husk (Metamucil) works by absorbing water and expanding into a thick, heavy gel mass

Second, in humans with loss-of-function variants in SLC22A1, which decrease the uptake of metformin into the liver, the ability of metformin to lower A1c levels is not impaired (48)

patients with symptoms of cholecystitis or choledocholithiasis require appropriate evaluation Acute kidney injury : Reported primarily in association with severe gastrointestinal adverse effects leading to dehydration

This is exactly why personalized care matters theres no one best medication for everyone