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Journal of Obesity & Metabolic Syndrome

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after stopping the medication, participants regained two-thirds of the prior weight loss at 1 year from time of withdrawal [73]

Serious but rare adverse effects include: Acute pancreatitis (patients should be advised to seek immediate medical attention for severe, persistent abdominal pain) Gallbladder disease, including cholecystitis and cholelithiasis Acute kidney injury, particularly in the context of dehydration from gastrointestinal side effects Hypoglycaemia, especially when used alongside other glucose-lowering medications Thyroid C-cell tumours (observed in rodent studies

Two repeat-dose studies were performed: a 4-week study with a 4-week recovery phase and a 26-week study