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Therefore, complex mechanisms in both neurons and astrocytes may be involved in GLP-1-induced modulation of food intake in the NTS

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When prescribing AOMs in older adults, consideration of drug-drug interactions should be sought in light of polypharmacy [76], as well as side effects, either directly through the pharmacological properties of the AOM, or indirectly through rapid and maintained weight loss, that may be amplified in older adults

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