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Analogs of GLP-1 have emerged as attractive diabetes treatments because of their favorable safety and efficacy profiles in lowering blood glucose levels through pancreatic betacellmediated glucosedependent insulin secretion and suppression of glucagon release

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This impaired contractility contributes to bile stasis, a situation in which bile remains in the gallbladder for prolonged periods, increasing the likelihood of cholesterol crystallization and gallstone formation

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