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International Journal of Molecular Sciences, 23(2), 739

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Duration Guidelines Based on Clinical Evidence Current medical guidelines recommend continuing GLP-1 therapy indefinitely for patients with obesity or weight-related metabolic conditions, similar to how blood pressure or cholesterol medications are managed long-term

In contrast, semaglutide at a dose of 2.4 mg per week for 68 weeks resulted in a 14.915.6% weight loss in non-diabetic individuals with overweight or obesity, also with an average BMI of approximately 38 [11, 12], demonstrating a stronger anti-obesity effect with semaglutide than with liraglutide

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