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In July 2024, Roche, a Swiss-based pharmaceuticals company, acquired Carmot Therapeutics for US$ 2.7 billion (with up to US$ 400 million in additional milestone payments)

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Conclusively, research on GLP-1R and its agonists marks a promising direction in metabolic disease therapy, extending their potential beyond glucose regulation and offering hope for more comprehensive approaches in addressing metabolic diseases

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Early evidence also suggests benefits in reducing liver fat and inflammation, which can help those with conditions like non-alcoholic fatty liver disease (NAFLD). What Are GLP-1 Supplements

In vivo studies conducted on animal models of MASLD/MASH have reveal that GLP-1RAs can reduce liver fibrosis scores and collagen deposition, accompanied by decreased inflammatory infiltration and oxidative stress (24, 32)