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Here is what the clinical data suggests for different starting BMI categories
Semaglutide is less effective at reducing body weight in T2D patients compared to patients without (5% weight loss, SUSTAIN-6 and 15% weight loss, STEP, respectively)

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Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns

Your individual needs will depend on your weight, height, age, gender, activity level, and weight loss/maintenance goals

GLP-1 medications have been shown to help people lose a significant percentage of body weight when paired with a healthy diet and regular exercise
