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A microscopic view of the hindbrain reveals support cells (highlighted in green, red, yellow and purple) that produce appetite-suppressing molecules

By including all English-language studies on muscle mass loss during GLP-1RA therapy in T2D and obesity from major scientific databases and clinical trial registries, this narrative review synthesizes the current knowledge on the epidemiology and mechanisms of muscle loss in diabetes and obesity, with a focus on the impact of GLP-1RAs therapy