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The result for some people is loose stools, cramping, or sudden urgency

A study analyzing the data from the US Department of Veterans Affairs database found that male patients with T2D (majority Caucasian males) who initiated GLP-1 medicines ( n = 215,970) had a lower risk of seizure (HR: 0.90, 95% CI: 0.850.95) compared to patients who continued the use of other glucose-lowering drugs (GLDs) ( n = 1,203,097) over a median of 3.68 years

Prevents continued benefit and requires cycling to restore normal sensitivity

Within the GLP-1 RA + CKD group, eGFR reduced from 50.1 ml/min per 1.73 m 2 to 44.8 ml/min per 1.73 m 2 at 5 years

A healthcare provider familiar with your complete medication list and metabolic history should evaluate whether combination therapy is appropriate for your specific situation