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Research has indicated that HPA axis hyperactivity is heightened in chronic hyperglycemic states, with severe hyperglycemic events more likely to result in depressive disorders [71]

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Safety, tolerability, and efficacy of NLY01 in early untreated Parkinson's disease: a randomised, double-blind, placebo-controlled trial

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H., & Koos, R

[ FDA News Release, March 8, 2024