glp-1 news nov 2025 November in review: breakthroughs, UPFs under fire, Novonesis advances healthy longevity Poll: 1 in 8 Adults

Basal receptor activation by locally produced glucagon-like peptide-1 contributes to maintaining beta-cell function

Glinides allow minimal dose titration and have an immediate onset of action and short duration of effect, which adapts to the hyperglycaemic profile of the corticosteroids and reduces the risk of hypoglycemia in the morning, coinciding with the disappearance of the hyperglycemic action of corticosteroids[25]

Months 23: Visible Results This is where results really pick up

Discussion Aside from the top 10% of responders in our real-world study, we found that GLP-1s resulted in smaller reductions in both weight loss and HbA1c, respectively

This agonist triggers the natural hormone our bodies produce that helps us feel full after eating, leading to less frequent hunger cues, a slower digestive rate, and, potentially, fewer blood sugar changes

Therapeutic effects of Glp-1 receptor agonists and Dpp-4 inhibitors in neuropathic pain: mechanisms and clinical implications