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Pharmacological inhibition of the NLRP3 inflammasome suppressed PFKFB3-driven glycolysis and vice versa, resulting in decreased lactate production in TGF-1+IL-1-stimulated lung fibroblasts

One of the largest real-world analyses in T2DM More than 64,000 participants Evaluated a practical "everyday clinic" decision rather than an idealized RCT scenario Compared therapy intensification versus complete therapeutic switch Reflected real-world dose titration patterns and clinician behavior

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Appetite & weight-related signaling

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Link to full post: GLP-1 Drugs, Digital Health & Obesity Trends in 2026Overweight and obesity are driving a booming digital health market through telehealth, wearables, and new pharma-to-consumer models.I've been reporting on this space in my #Trends report since March 2024two years ago (Navigating Obesity Care in the Digital Age)