most common side effects of glp-1 GI Adverse Glucagon-Like Peptide-1 Receptor Agonists GLP-1 drugs can cause pancreatitis,

Animal studies

Your cells become "deaf" to insulin's signals, so your body pumps out more and more insulin to compensate

Alberto Ortiz made substantial contributions in the design of the work, bibliographic search, drafted the manuscript, reviewed the manuscript, interpretation, discussion and conclusions, provided intellectual senior input, contribute to text and contents of the manuscript including revisions and edits and approve of the content of the manuscript and agree to be held accountable for the work

doi: 10.1038/nm919

Weight loss results are not guaranteed, and some patients may experience minimal or no weight loss despite treatment compliance

As future doctors, we are taught to always warn patients on sulfonylureas about hypoglycemia symptoms shakiness, sweating, confusion and to always carry sugar with them. Mohammad Junaid Rain, MBBS 2nd Year Key advantages of Sulfonylureas: Very affordable 30100/month in India Available everywhere even in small town pharmacies Strong blood sugar lowering effect Decades of safety data Key disadvantages: Hypoglycemia risk can cause dangerous low blood sugar Weight gain 24 kg on average Beta cell burnout with long term use, pancreas gets more exhausted Not ideal for elderly patients or those who skip meals Hypoglycemia warning signs to tell your patients: What to do: Immediately eat 23 teaspoons of sugar or drink a glass of fruit juice