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PLoS ONE 8 , e84569 (2013)

The first and original use is for type 2 diabetes management , where GLP-1 agonists help lower hemoglobin A1c levels by 1.02.0% on average, with the additional benefit of promoting modest weight loss rather than weight gain seen with some other diabetes medications

However, such boxed warnings stem from decade-old rodent research, Chiang said

It is essential to consult with a qualified healthcare provider or physician for any inquiries related to a medical condition, treatment, or before initiating any new healthcare routines

In: Avers D, Wong RA, editors

Your provider may recommend starting oral therapy at a maintenance dose rather than the lowest starting dose if you have already been on therapeutic GLP-1 doses via injection