asa glp-1 agonists and Anesthesia: Considerations and Cautions for CRNAs Evolving Role of Double and
Description
Here is what a typical 6-week drug holiday timeline looks like based on pharmacokinetic data and clinical reports

doi: 10.1124/pr.115.011395 [DOI] [PMC free article] [PubMed] [Google Scholar] 8

They may not be appropriate for people with certain medical conditions, and they may not be the best choice for people looking for short-term weight loss only

What other interactions do you think are important to highlight for patient safety
for example, 3 kg weight reduction leads to a marginal improvement in LDL-C and mean reduction in triglycerides of 15 mg/dL, while weight loss of 58 kg, lowers LDL-C on average by 5 mg/dL and increases HDL-C by 3 mg/dL

Theres also a small risk of gallbladder-related issues, especially with rapid weight loss
