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Glucose-dependent insulinotropic polypeptide (GIP) is secreted by enteroendocrine K cells, primarily located in the upper small intestine, in response to food intake and plays a significant role in the postprandial regulation of nutrient metabolism
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Metabolic tracing of the isolated intestinal crypts further suggested that fructolysis activity is coupled to the ATP/ADP ratio in the L-cell-resident niche
