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Administered through a once-weekly injection, it assists adults with a BMI of 30 or higheror 27 or higher with related health conditionsfacilitating significant weight loss

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These mechanisms help explain why GLP-1s appear to trigger a significant 12% to 18% weight loss on average

The hindbrain receives satiety signals from the body via GLP-1R and preproglucagon (PPG) neurons that express the gene gcg, which sends endogenous GLP-1 throughout the brain [69]

Over that timeframe, small habits compound into significant differences in outcomes, comfort, and safety

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