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The equations and criteria for these algorithms (Supplementary Table S2

doi: 10.3390/biom13091332 Summary Keywords GLP-1 receptor agonists, Sepsis, muscle atrophy, inflammation, oxidative stress Citation Dimic N, Djuric M, Vejapi M, Nenadic I, Bobos M, Bojic S, Savic P, Milanovic M and Stevanovic P (2025) The role of GLP-1 in the pathophysiology and treatment of sepsis: a narrative review

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In large studies, GLP-1 therapies reduced body weight by an average of 4.57 kg, body mass index by 2.07 kg/m, and waist circumference by 4.55 cm compared with placebo

Key areas of investigation include optimal timing of initiation, identification of responsive subgroups of patients, and evaluation of synergistic effects when combining GLP-1RAs with established biologics

( 10.1016/j.appet.2018.05.131) [DOI] [PMC free article] [PubMed] [Google Scholar] 94.Gilroy CA, Capozzi ME, Varanko AK, Tong J, DAlessio DA, Campbell JE, Chilkoti A
