who is not a candidate for semaglutide What BMI Do You Need to Qualify GLP-1? Considering Semaglutide for Weight Loss:

Last week, drugmaker Eli Lilly announced results from a late-stage diabetes trial showing that its daily GLP-1 pill orforglipron significantly reduced A1C (a measure of blood sugar) and body weight compared with placebo (a sham pill)

HabibAMRichardsPCairnsLSRogersGJBannonCAParkerHEet al

Additionally, the metabolic changes driven by GLP-1 receptor agonists promote steady, long-term weight loss, which is particularly helpful for those dealing with insulin resistance and hormonal imbalances

A 12-week medication course addresses none of these underlying drivers in a permanent way

Although Rybelsus is not approved for weight loss specifically, your healthcare professional may prescribe the drug off-label for this purpose, even if you do no have type 2 diabetes

Safety Information: What Belongs in Your Conversation With a Provider Before You Start Do not use compounded GLP-1 medications if you have: a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)