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Description
Effect of weight loss on cardiometabolic risk: observational analysis of two randomised controlled trials of community weight-loss programmes
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Mol Endocrinol (1996) 10(4):34255

In both the trial-product and treatment-policy estimand analyses, all oral semaglutide groups demonstrated a significantly greater reduction in A1C from baseline when compared with placebo at 26 and 52 weeks

Metformin (1,1-Dimethylbiguanide hydrochloride, Sigma-Aldrich

Then GLP-1 medications hit the market
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Glucagon-Like Peptide-1 (GLP-1) Analogues
