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By the end of the study, around half of participants were on SGLT2 inhibitors

A frequentist framework was employed using the netmeta 3.2, R 4.5 package to synthesise both direct and indirect evidence from RCTs evaluating the efficacy, safety, and treatment discontinuation of dual and triple GLP1 receptor agonists in adults with obesity and/or T2DM [28]

Among these factors, only tumor multifocality was significantly negatively correlated with GLP-1R expression in both univariable and multivariable analyses

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If nausea is problematic with injectable semaglutide, oral semaglutide (starts at $249/mo) may be better tolerated by some patients