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If symptoms are particularly troublesome, your doctor may recommend: Slower dose escalation than standard protocols Temporary dose reduction Switching to a different GLP-1 agonist, as individual responses vary Short-term use of anti-diarrhoeal medications such as loperamide for acute episodes, though this should only be done under medical supervision and avoided if you have blood in your stool, fever, or suspected infection If you're also taking insulin or sulfonylureas, monitor your blood glucose more frequently during periods of reduced appetite or diarrhoea, as you may need dose adjustments to prevent hypoglycaemia

Risk of serotonin syndrome: The combination can increase the risk of serotonin syndrome, a rare but life-threatening condition

Social media has become a common way for people to share their GLP-1 journeys, and for others to purchase the medicine

doi:10.1056/NEJMoa2028198 Obesity Medicine Association

Use the right type of water (bacteriostatic, not sterile water for injection, which lacks the preservative)

Most hotels provide one upon request, and some have them standard