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Description
Most prescribing guidelines recommend 8 to 12 weeks of treatment, followed by a break
Mild nausea, if present, typically resolves within the first week
Additionally, magnetic resonance imaging (MRI) conducted on a subset of participants from the SURPASS-3 trial showed that, after 52 weeks of treatment with tirzepatide, liver fat content was reduced by 30% or more in 67% to 79% of participants, and VAT volume decreased by 16% to 25% [62]
Patients experiencing persistent gastrointestinal side effects that interfere with daily activities or nutritional intake may benefit from extending the duration at each dose level beyond the minimum four weeks before attempting further escalation
The bioavailability is unknown
References SingleCare
