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JAMA 2022;327:13850

Recently, Taraschi et al

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In clinical studies, while the direct effects on -synuclein aggregation in humans are still being investigated, improvements in motor function, cognitive abilities, and general neuronal health have been observed, suggesting that GLP-1 RAs are impacting these pathological processes

doi: 10.1126/scitranslmed.3007218, 30
(2021) study identified a specific protein produced by Akkermansia muciniphila that stimulates GLP-1 release from intestinal L-cells
