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Description
A randomised controlled trial in 1,897 individuals living with type 2 diabetes compared the impact of three doses of tirzepatide (5mg, 10mg, and 15mg) compared to a once-weekly injection of 1mg semaglutide (Ozempic) on blood sugar levels
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Optical coherence tomography Change in pRNFL thickness was not associated with the treatment group but with pRNFL thickness at baseline (M3: \(\beta\)= 0.32, 95% CI 0.41, 0.23

He lost 10 lbs, then gained 20

Conducted between June 2011 and March 2013 at 191 sites in 27 countries in Europe, North America, South America, Asia, and Australia this was a randomised, placebo-controlled trial designed to evaluate the efficacy and safety of 3mg liraglutide 'injected subcutaneously once daily, as an adjunct to a reduced-calorie diet and increased physical activity, for weight management in overweight or obese adults who did not have diabetes at baseline.' A total of 3,731 individuals participated in the trial, of whom 2,487 were assigned to lifestyle intervention plus liraglutide and 1,244 to lifestyle intervention with a placebo

doi: 10.1136/gut.24.2.114
