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Lifestyle factors such as diet, tobacco use, excessive alcohol consumption, and obesity can also contribute to an increased risk

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Cagrilintide's amylin mechanism produces postprandial glucagon suppression independent of glucose level, complementing the GLP-1 component

5 Discussion The safety and efficacy of GLP-1RAs in the treatment of type 2 diabetes have been well demonstrated

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Studies of HFrEF patients raised questions about the safety profile of GLP-1RA therapy in this subpopulation