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The most common side effects of GLP-1 medications include nausea, vomiting, diarrhea, and constipation

Animal studies of tirzepatide suggested possible fetal harm, though human data are lacking

GLP-1RAs are a relatively new class of injectables that are effective at reducing HbA 1c , have a low risk of hypoglycaemia when given as monotherapy or in the absence of sulphonylureas (SU) or insulin, and have the potential for weight losskey considerations when treating a typical obese patient with T2DM [4]

doi: 10.1136/jim-2021-001952 [DOI] [PMC free article] [PubMed] [Google Scholar] 48.Novo Nordisk

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Brain Res