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Unlike extreme programs that force drastic changes overnight, glp 1 works with the body to create gradual improvements

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GLP-1Rs agonists exert neuro-humoral actions by stimulating insulin secretion and suppressing glucagon release in a glucose-dependent manner, delaying gastric emptying, and reducing appetite via central nervous system pathways

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These numbers suggest a dose-dependent relationship, though individual variation means some people on lower doses still experience significant constipation while others on the full 12mg dose never develop issues