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Zhang Y, Zhang J, Wang Q, et al
Tachyphylaxis is contingent upon a full 24-hour exposure, as evidenced by a study in which rats treated with liraglutide (with half-life of 11 15 hours) twice daily for 14 days had markedly diminished gastric emptying while those treated with exenatide (with half-life of 2 3 hours) twice daily over the same period still displayed a profound reduction in gastric emptying, although both compounds had similar effects on body weight reduction (158)
Always use prescribed medications with the support of a GPhC-registered healthcare professional
Administration: The pen is designed for subcutaneous injection, typically in the abdomen, thigh, or upper arm
Chen SD, et al
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