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The tri-agonist treatment prevented excessive weight gain in vehicle-treated mice to a greater degree than the GLP-1/GIP coagonist, and this observation was not due to any alterations in cumulative food intake

Last updated on Apr 27, 2026

Based on coverage patterns for similar medications (semaglutide, tirzepatide), expect the following landscape in Canada

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Most gastrointestinal side effects such as bloating and gas are mild and self-limiting, typically resolving within days to weeks as the gut microbiome adjusts to the introduced bacterial strains

And maybe here is a good place to spell out just how long the development and approval process for these drugs can be