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It has not yet been assessed for use on the NHS

Certain effects, like appetite suppression, can still occur at low doses, while others, like substantial weight loss or blood sugar changes, require higher dosing, she says

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Reducing the dose without medical advice can lead to inadequate control of the condition , leading to potential complications

References: Retatrutide, a GIP, GLP-1 and Glucagon Receptor Agonist, for People With Type 2 Diabetes: A Randomised, Double-Blind, Placebo and Active-Controlled, Parallel-Group, Phase 2 Trial Conducted in the USA

If anything on the COA feels unclear or worrying, it is reasonable to ask your pharmacist or prescriber to explain it in plain language