surmount-1 tirzepatide trial obesity without diabetes SURMOUNT-4 results just published in @JAMA_current 🛑Stopping #tirzepatide leads to regain of the majority of the lost weight. Is this a surprising result ⁉️ No #Obesity is a chronic disease and requires 💊 Could a new medication

Evidence suggests that these mechanisms are the key to weight loss: The beneficial effects of tirzepatide on body composition and blood sugar levels can all contribute to a healthy heart

Gerber (Johns Hopkins University) as study physicians

A study of tirzepatide (LY3297176) compared with placebo in adults with type 1 diabetes and obesity or overweight (SURPASS-T1D-1)

Some common alternatives to tirzepatide for type 2 diabetes include: Metformin: A widely used oral medication that helps lower blood sugar levels by reducing the production of glucose in the liver and improving insulin sensitivity

Semaglutide GLP-1 is known as a GLP-1 receptor agonist

"We are excited to share that the Zepbound single-dose vials are now here, further delivering on our promise to increase supply of Zepbound in the U.S.," said Patrik Jonsson, executive vice president, and president of Lilly Cardiometabolic Health and Lilly USA