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For researchers with a history of gallbladder problems, existing gallstones, or other biliary risk factors like rapid previous weight loss episodes or high BMI, this difference should factor into their medication choice

This may or may not include tapering off a GLP-1

When combined with healthy lifestyle changes, they may support long term weight management

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These weight losses are even more pronounced in people who are obese but do not have diabetes (Figure 5)

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