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No evidence of cardiac, hepatic, or renal toxicity, changes in serum lipids, or clinically relevant changes in laboratory parameters, vital signs, electrocardiograms, or abnormal findings upon physical examinations have been observed

Cardiovascular-risk coverage under private plans in So Paulo already rose in 2025, and Mexicos ISSSTE is examining similar add-on benefits for 2027

Once things calm down, you can usually restart at the same or a lower dose

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However, analysts anticipate a decline in Paxlovid sales in 2025 due to a smaller US winter COVID wave and reduced government purchases