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Additionally, as weight is lost, hunger hormones (like Ghrelin) increase while fullness hormones (such as GLP-1, CCK, and Leptin) decrease, leading to increased hunger

Owing to the recent increase in the prevalence of prediabetes, diabetes, obesity, and abdominal obesity among young adults under the age of 40 [1,7], there have been suggestions for a change in previous screening criteria for diabetes (adults aged 40 and adults aged 30 years with risk factors) [2]

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Beyond that, the causes vary

The BMI used is your BMI at the time you first started GLP-1 therapy, not your current BMI

Understanding how these medications behave in your system, from initial dosing through to maintenance therapy, helps clarify what to expect during treatment and why gradual dose escalation is standard practice in UK clinical care