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2025;8(1):e2457232-e

In our analysis, a trend towards a decreased risk of sleep apnea syndrome was found with the use of GLP-1RA (RR 0.86, 95% CI 0.501.45)

The mechanisms underlying taste perception changes during GLP-1 therapy are likely multifactorial and indirect rather than representing true gustatory dysfunction

Metformin works primarily by reducing hepatic glucose production (the amount of glucose released by the liver), improving insulin sensitivity in peripheral tissues, and modestly enhancing glucose uptake in muscles

Abstract Metformin is an effective agent with a good safety profile that is widely used as a first-line treatment for type 2 diabetes, yet its mechanisms of action and variability in terms of efficacy and side effects remain poorly understood

F., Okamura T., Brning J
