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In clinical trials, nausea affected approximately 12 to 18 percent of participants at the 2.5 mg starting dose, rising to 24 to 29 percent at higher therapeutic doses

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Bollag RJ, Zhong Q, Phillips P et al (2000) Osteoblast-derived cells express functional glucose-dependent insulinotropic peptide receptors

It has been modified so that DPP-4 cannot metabolize it

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