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Clinical nutrition guidelines recommend that patients on weight loss therapy engage in regular physical activity and consume sufficient protein to help preserve muscle mass

Abstract Sodium-glucose co-transporter 2 (SGLT2) inhibitors are glucose-lowering drugs that reduce plasma glucose levels by inhibiting glucose and sodium reabsorption in the kidneys, thus resulting in glucosuria

10.1016/j.molmet.2017.05.002 107 ShinN.-R.LeeJ.-C.LeeH.-Y.KimM.-S.WhonT

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This is likely the biggest factor in inducing weight loss