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Adverse Reactions in the Clinical Trials of Adults with Type 2 Diabetes Mellitus Pool of Two Placebo-Controlled Clinical Trials in Adults The data in Table 1 are derived from 2 placebo-controlled trials [1 monotherapy trial (SURPASS-1) and 1 trial in combination with basal insulin with or without metformin (SURPASS-5)] in adult patients with type 2 diabetes mellitus [see Clinical Studies (14.2, 14.4)]

Developing an oral formulation of semaglutide has required years of research, innovation, and clinical development

Many primary care practices have integrated GLP-1 therapy into their metabolic wellness programs, though some remain cautious about off-label use

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