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Sandoz and Apotex are also preparing for potential early 2026 launches, with Biocon targeting late 2026/early 2027 in Canada as part of a broader push into emerging markets

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Clinical trials and pooled analyses have shown that the combination has a safety profile similar to each component alone, with a low incidence of hypoglycemia (unless combined with insulin or sulfonylureas)

This umbrella review synthesizes the evidence for safety and efficacy GLP-1 receptor agonists on multiple outcomes including but not limited to metabolic, cardiovascular and renal outcomes.