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But is the connection direct, or is it the extreme weight loss and lack of sustenance pulling the trigger

The same way insulin manages diabetes
Dermatologists can perform scalp examination, hair pull tests, or scalp biopsy if needed to establish a definitive diagnosis

doi: 10.7759/cureus.52564
A related question is whether GLP-1s, when combined with a mindfulness practice, facilitate the adoption and maintenance of mindfulness more easily than training alone, and whether or not a combined program of GLP-1 and mindfulness yields greater or more sustained weight loss post-GLP-1 removal than either a pharmacotherapy program or a mindfulness program alone

GLP-1 receptor agonists enhance regulatory T cell function